"One of the main proposed mechanism of actions is based upon production of transient pores in adipocytes, allowing lipids to leak out. Another is through activation of the complement cascade which could cause induction of adipocyte apoptosis and subsequent release of lipids.
LLLT may also aid autologous fat transfer procedures by enhancing the viability of adipocytes.
While after 4 minutes of laser exposure 80% of the fat was released from the adipose cells, after 6 minutes of laser exposure almost all of the fat was released from the adipocyte. When no tumescent solution was applied and adipose tissue was exposed to laser beam for 4 and 6 minutes, scanning electron microscope (SEM) and transmission electron microscope (TEM) images after 6 minutes laser exposure in samples taken without tumescent solution corresponded to those observed in samples exposed to 4 minutes of laser irradiation with equal parameters and the tumescent solution. Without laser exposure and only tumescent technique, the adipose tissue remained intact and adipocytes maintained their original spherical structure.